Instructions
for use

MOTS-c

Pharmacological properties

MOTS-c (mitochondrial derived peptide MDP-s, Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded by mitochondrial DNA. It is involved in regulating energy metabolism, glucose and lipid metabolism, and cellular stress responses. The peptide activates AMPK (adenosine monophosphate-activated protein kinase), a key regulator of cellular energy balance. MOTS-c is a promising peptide in the context of metabolism control, aging, endurance, longevity, and processes leading to diseases such as osteoporosis.

Composition

1 vial (3 ml) contains:

MOTS-c – 15 mg

Water for injection

Indications for use

MOTS-c reduces body weight, promotes fatty acid oxidation, and improves insulin sensitivity: MOTS-c increases glucose uptake by muscles, activates AMPK, and raises GLUT4 transporter levels.

Anti-aging effects: Increased MOTS-c levels in the blood improve physical activity, reduce inflammation, and enhance endurance in adulthood.

Contraindications

Hypersensitivity to MOTS-c or excipients

Pregnancy and lactation (due to lack of sufficient clinical data)

Children under 18 years (lack of sufficient clinical data)

Dosage and Administration

Subcutaneously, with a standard insulin syringe — 1 ml / 100 units

Subcutaneous Injection Regimen

Vial

15 mg / 3 ml

Шприц

1 мл / 100 units

Разова доза

50u=2.5 mg

Частота

раз в 6 днів

Single dose

50u=2.5 mg

Frequency

once every 6 days

Administration time

morning/day

Injections per vial

6 injections (2.5mg)

Vials per course

1-2 vials

Administration Rate

30–60 sec/0.1 ml

Rotate injection sites

abdomen, shoulder, thigh, buttock

One bottle lasts approximately 6 weeks

Possible adverse reactions

Possible:

Erythema, itching, induration.

Systemic:

headache, dizziness, dyspepsia.

In case of severe reactions, discontinue therapy and provide symptomatic treatment.

Special instructions

Gradually titrate the dose.

Administer in the first half of the day, 1–1.5 hours after a meal.

In case of adverse reactions, adjust dose or temporarily discontinue.

Store opened vial at 2–8°C, use within one month.

Storage conditions

Store at 2–8°C, out of reach of children and protected from light.

Do not freeze.

Shelf life

The shelf life of the NAD+ product is 24 months from the manufacturing date, provided it is stored at 2–8°C. Do not use after the expiration date indicated on the packaging.

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